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Bioreactor and Fermenter Systems

LAB1ST engineers a full-spectrum reactor platform in glass and stainless steel, supporting modular expansion, multi-parallel operation and cascade process configurations. With decades of process expertise and proven scale-up experience from laboratory development to industrial production, we deliver turnkey bioprocess engineering solutions trusted by partners in over 40 countries worldwide.

Advantages

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Broad Compatibility Across Diverse Applications

LAB1ST bioreactors comply with GMP standards and support diverse bioprocessing needs, from mammalian and stem cell cultures to yeast and bacterial fermentation. With flexible configurations of vessel types, gas supply, agitation, and feeding strategies, the systems provide optimized culture conditions for diverse cell types.

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Seamless Scale-Up from R&D to Production

The product portfolio covers a wide working volume range from 0.5 L to 1000 L, enabling seamless transition from laboratory research and process development to pilot and commercial-scale production. Streamlined scale-up capabilities accelerate process transfer and industrialization.

 

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Precision Control for Data-Driven Process Optimization

LAB1ST systems enable real-time monitoring and intelligent control of critical process parameters, including pH, DO, temperature, and nutrient supply. Advanced process control ensures consistent, stable, and reliable cultivation performance.

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Integrated Solution, End-to-End Support

With 30 years of industry experience, LAB1ST is capable of delivering large-scale bioreactor projects up to 120 tons with complete one-stop solutions. The portfolio includes supporting equipment such as steam generators, CIP stations, autoclaves, and upstream/downstream processing machines for seamless workflow integration.

Glass Bioreactor

All Models
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BR100

Entry-Level Glass Bioreactor

Vessel volume: 1 – 15L

Built-in fixed-speed peristaltic pumps; rotameter-controlled gas flows​

Easy-to-read 10.1“ touchscreen interface

Single or twin vessel configuration​​​​

Models

BR100-C1/C2              Cellular

BR100-M1/M2             Microbial

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BR200e

Next-Gen ​Economical Bioreactor

Interchangeable vessel: 1 – 15 L

 

Built-in variable-speed peristaltic pumps; rotameter-controlled gas flows

 

Upgraded Siemens S7 1200 PLC controller + 22" industrial resistive touchscreen

 

Supports single, twin or multiple vessel  configuration 

Models

BR200e-C1/C2          Cellular 

BR200e-M1/M2         Microbial

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BR100Pro

Advanced Glass Bioreactor

Interchangeable vessel: 3 – 15 L

Built-in variable-speed peristaltic pumps; Precision MFC-controlled gas flows

15.6” industrial resistive touchscreen

Single or twin vessel configuration​​​​

Models

BR100PRO-C1/C2      Cellular

BR100PRO-M1/M2     Microbial

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BR100PRL

Parallel Glass Bioreactor

3-6 parallel vessels [same size]: 0.5 – 15 L

 

Built-in stainless steel shelving and cabinetry simplify installation and operation

 

Easy-to-read 10.1“ touchscreen interface

 

Supports online sterilization (SIP), enabling continuous operation with minimal downtime

Models

BR100PRL-C3~6        Cellular

BR100PRL-M3~6       Microbial

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BR200

Next-Gen Glass Bioreactor

Interchangeable vessel: 1–15 L

Watson Marlow variable-speed peristaltic pumps; independent MFC-controlled gas flows

Upgraded Siemens S7 1200 PLC controller + 22" industrial resistive touchscreen

 

Supports single, twin or multiple vessel  configuration 

Models

BR200-C1/C2              Cellular

BR200-M1/M2             Microbial

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BR110

High-Throughput Glass Bioreactor

Up to 8 parallel vessels [same size]: 0.7 – 15 L

 

Built-in variable-speed peristaltic pumps; rotameter-controlled gas flows

 

Upgraded Siemens S7 1200 PLC controller + 15.6" touchscreen

 

Vessel heating and cooling by stainless steel base

Models

BR110-C                      Cellular

BR110-M                     Microbial

SCADA Control System

Parallel processing up to 8 vessels

Remote operation and real-time data visualization​

Integrated process monitoring and flexible recipe management

GMP-compliant data integrity and 21 CFR Part 11 ready

Compatible with BR200/BR200e benchtop bioreactor series

Stainless Steel Bioreactor

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BR500

Entry-Level Stainless Steel Bioreactor

Single vessel: 10 L – 500 L

 

Built-in fixed-speed peristaltic pumps; rotameter-controlled gas flows

 

Easy-to-read 10.1“ touchscreen 

 

All-in-one skid-mounted design, small footprint and easy to move​​​​​

Models

BR500-C1/C2              Cellular 

BR500-M1/M2            Microbial

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BR500Pro

Advanced Stainless Steel Bioreactor

Interchangeable vessel: 10 L – 1000 L

 

Built-in variable-speed peristaltic pumps; Precision MFC-controlled gas flows

 

15.6” industrial resistive touchscreen

 

Single or twin vessel configuration

Models

BR500PRO-C1/C2       Cellular 

BR500PRO-M1/M2      Microbial

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BR500PRL

Parallel Stainless Steel Bioreactor

2-6 parallel vessels [same size]: 10 L – 1000 L

Built-in fixed-speed peristaltic pumps; rotameter-controlled gas flows

 

Easy-to-read 10.1“ touchscreen 

 

 All-in-one skid-mounted design, small footprint and easy to move

Models

BR500PRL-C2~6       Cellular 

BR500PRL-M2~6      Microbial

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BR500CCD

Cascade Stainless Steel Bioreactor

Incremental vessel sizing from small (10 L) to large, designed for process scale-up

 

Independent environmental conditions and setting parameters per stage

 

Vessel volumes and stage count configurable to process needs

 

Application for cell culture and microbial fermentation

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BR500SSB

Solid State Stainless Steel Bioreactor

Vessel capacity: 5 L – 2000 L

 

Low-moisture environment suited to fungi and certain bacteria

 

Cost-effective on inexpensive substrates, which are often derived from agricultural and industrial waste

 

High product stability due to the low-moisture environment

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BR500ALB

Airlift Stainless Steel Bioreactor

No mechanical agitation — fluid circulation via gas lift

 

Efficient gas-liquid dispersion with low power consumption

 

Low shear, with homogeneous shear and stress distribution throughout the entire vessel

 

Excellent liquid-solid and gas-liquid mass transfer efficiency

Single-Use Bioreactor

SUB100

Benchtop Single-Use Bioreactor

Volume Capacity: 5 L – 100 L

Pre-sterilized, no cleaning validation required

Online measurement of DO and PH

Applications: human, mammalian, and other shear or stress-sensitive cells

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SUB500

Floor-Standing Single-Use Bioreactor

Fully scalable from pilot to industrial scale: 50 L – 2000 L

Easy to set up, operate and maintain

Built with a unique upward-inclined stirrer

Applications: human, mammalian and other cells

Applications

Cell & Gene Therapy

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Biologics Production

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Vaccine Development

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Microbial Fermentation

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Functional Food Ingredients

Custom Configuration Guide

1

Architecture

  • Single / twin / parallel vessel

3

Agitation

  • Impeller

  • Speed

  • Sealing

5

Liquid Feed

  • Variable-speed / fixed-speed pumps

  • Automatic feeding 4-valve manifold

6

Communication & Automation

  • PLC & HMI

  • SCADA

7

Basic Monitoring

  • pH

  • DO

  • Temp.

  • Foam

2

Vessel Config

  • Material

  • Size & aspect ratio

  • Wall

  • Heating options

  • Lighting module

4

Gas System

  • Gas supply

  • MFC

  • Rotameter

  • Sparger

8

Advanced Process Analytics

  • OD

  • DCO2

  • VCD

  • ORP

  • Off-gas analysis & heating

  • Weighing Module

  • Aseptic sampling device

  • Level detection

Supporting Equipment

CIP Station

Autoclave

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Air compressor

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Steam Generator

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Chiller

Service & Support

Onsite Installation and Training

Complete Production and Inspection Process

30+ Years Experience of Biotech Engineering Team

Customization Capability

Contact us

Need to speak to a LAB1ST expert? Please complete the form below for your general request, product or service inquiry.

LAB1ST logo

LAB1ST Group is offering equipment, solution and services to worldwide customers in various industries.

We aim to be your first-choice supplier.

Labfirst Scientific Instruments (Shanghai) Co., Ltd.

Sales Department: Building 6, No. 248 Guanghua Road, Minhang District, Shanghai, China
(Registered Address: Room 1252, Building 1, No. 215 Lianhe North Road, Fengxian District, Shanghai, China)

Laiyuan Scientific Instruments (Shanghai) Co., Ltd.

Room 101, Building 31, No. 248 Guanghua Road, Minhang District, Shanghai, China

LABFIRST INDUSTRIES CO., LIMITED

RM 12, 20/F, HO KING COMM CTR, 2-16 FA YUEN ST, MONGKOK, KL, Hong Kong

CALPHA INDUSTRIES INC.

​10 CORPORATE PARK STE 330, IRVINE, CA 92606, USA

LSI PROCESS EQUIPMENT CO., LTD.

​701 West Georgia Street, Suite 1500, Vancouver, British Columbia, V7Y 1C6, Canada

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