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Bioreactor and Fermenter Systems

LAB1ST engineers a full-spectrum reactor platform in glass and stainless steel, supporting modular expansion, multi-parallel operation and cascade process configurations. With decades of process expertise and proven scale-up experience from laboratory development to industrial production, we deliver turnkey bioprocess engineering solutions trusted by partners in over 40 countries worldwide.

Advantages

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Broad Compatibility Across Diverse Applications

LAB1ST bioreactors comply with GMP standards and support diverse bioprocessing needs, from mammalian and stem cell cultures to yeast and bacterial fermentation. With flexible configurations of vessel types, gas supply, agitation, and feeding strategies, the systems provide optimized culture conditions for diverse cell types.

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Seamless Scale-Up from R&D to Production

​The product portfolio covers a wide working volume range from 0.5 L to 1000 L, enabling seamless transition from laboratory research and process development to pilot and commercial-scale production. Streamlined scale-up capabilities accelerate process transfer and industrialization.

 

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Precision Control for Data-Driven Process Optimization

LAB1ST systems enable real-time monitoring and intelligent control of critical process parameters, including pH, DO, temperature, and nutrient supply. Advanced process control ensures consistent, stable, and reliable cultivation performance.

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Integrated Solution, End-to-End Support

​With 30 years of industry experience, LAB1ST is capable of delivering large-scale bioreactor projects up to 120 tons with complete one-stop solutions. The portfolio includes supporting equipment such as steam generators, CIP stations, autoclaves, and upstream/downstream processing machines for seamless workflow integration.

Glass Bioreactor

All Models
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BR100

Entry-Level Benchtop Bioreactor

✓ Vessel volume: 1 – 15L

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✓ Built-in fixed-speed peristaltic pumps; rotameter-controlled gas flows​

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✓ Easy-to-read 10.1“ touchscreen interface

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✓ Single or twin vessel configuration​​​​

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Models

BR100-C1/C2              Cellular

BR100-M1/M2             Microbial

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BR200e

Next-Gen ​Economical Bioreactor

✓ Interchangeable vessel: 1 – 15 L

 

✓ Built-in variable-speed peristaltic pumps; rotameter-controlled gas flows

 

✓ Upgraded Siemens S7 1200 PLC controller + 22" industrial resistive touchscreen

 

✓ Supports single, twin or multiple vessel  configuration 

Models

BR200e-C1/C2          Cellular 

BR200e-M1/M2         Microbial

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BR100Pro

Advanced Benchtop Bioreactor

✓ Interchangeable vessel: 3 – 15 L

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✓ Built-in variable-speed peristaltic pumps; Precision MFC-controlled gas flows

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✓ 15.6” industrial resistive touchscreen

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✓ Single or twin vessel configuration​​​​

Models

BR100PRO-C1/C2      Cellular

BR100PRO-M1/M2     Microbial

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BR100PRL

Parallel Glass Bioreactor

✓ 3-6 parallel vessels [same size]: 0.5 – 15 L

 

✓ Built-in stainless steel shelving and cabinetry simplify installation and operation

 

✓ Easy-to-read 10.1“ touchscreen interface

 

✓ Supports online sterilization (SIP), enabling continuous operation with minimal downtime

Models

BR100PRL-C3~6        Cellular

BR100PRL-M3~6       Microbial

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BR200

Next-Gen Benchtop Bioreactor

✓ Interchangeable vessel: 1–15 L

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✓ Watson Marlow variable-speed peristaltic pumps; independent MFC-controlled gas flows

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✓ Upgraded Siemens S7 1200 PLC controller + 22" industrial resistive touchscreen

 

✓ Supports single, twin or multiple vessel  configuration ​

Models

BR200-C1/C2              Cellular

BR200-M1/M2             Microbial

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BR110

High-Throughput Glass Bioreactor

✓ Up to 8 parallel vessels [same size]: 0.7 – 15 L

 

✓ Built-in variable-speed peristaltic pumps; rotameter-controlled gas flows

 

✓ Upgraded Siemens S7 1200 PLC controller + 15.6" touchscreen

 

✓ Vessel heating and cooling by stainless steel base

Models

BR110-C                      Cellular

BR110-M                     Microbial

SCADA Control System

✓ Parallel processing up to 8 vessels

​✓ Remote operation and real-time data visualization​

✓ Integrated process monitoring and flexible recipe management

​✓ GMP-compliant data integrity and 21 CFR Part 11 ready

​✓ Compatible with BR200/BR200e benchtop bioreactor series

Stainless Steel Bioreactor

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BR500

Entry-Level Stainless Steel Bioreactor

✓ Single vessel: 10 L – 500 L

 

✓ Built-in fixed-speed peristaltic pumps; rotameter-controlled gas flows

 

✓ Easy-to-read 10.1“ touchscreen 

 

✓ All-in-one skid-mounted design, small footprint and easy to move​​​​​

Models

BR500-C1/C2              Cellular 

BR500-M1/M2            Microbial

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BR500Pro

Advanced Stainless Steel Bioreactor

✓ Interchangeable vessel: 10 L – 1000 L

 

✓ Built-in variable-speed peristaltic pumps; Precision MFC-controlled gas flows

 

✓ 15.6” industrial resistive touchscreen

 

✓ Single or twin vessel configuration

Models

BR500PRO-C1/C2     Cellular 

BR500PRO-M1/M2    Microbial

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BR500PRL

Parallel Stainless Steel Bioreactor

✓ 2-6 parallel vessels [same size]: 10 L – 1000 L

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✓ Built-in fixed-speed peristaltic pumps; rotameter-controlled gas flows

 

✓ Easy-to-read 10.1“ touchscreen 

 

✓ All-in-one skid-mounted design, small footprint and easy to move

Models

BR500PRL-C2~6       Cellular 

BR500PRL-M2~6      Microbial

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BR500CCD

​Cascade Stainless Steel Bioreactor

✓ Incremental vessel sizing from small (10 L) to large, designed for process scale-up

 

✓ Independent environmental conditions and setting parameters per stage

 

✓ Vessel volumes and stage count configurable to process needs

 

✓ Application for cell culture and microbial fermentation

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BR500SSB

Solid State Stainless Steel Bioreactor

✓ Vessel capacity: 5 L – 2000 L

 

✓ Low-moisture environment suited to fungi and certain bacteria

 

✓ Cost-effective on inexpensive substrates, which are often derived from agricultural and industrial waste

 

✓ High product stability due to the low-moisture environment

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BR500ALB

Airlift Stainless Steel Bioreactor

✓ No mechanical agitation — fluid circulation via gas lift

 

✓ Efficient gas-liquid dispersion with low power consumption

 

✓ Low shear, with homogeneous shear and stress distribution throughout the entire vessel

 

✓ Excellent liquid-solid and gas-liquid mass transfer efficiency

Single-Use Bioreactor

SUB100

Benchtop Single-Use Wave Bioreactor

✓ Volume Capacity: 5 L – 100 L

✓ Pre-sterilized, no cleaning validation required

✓ Online measurement of DO and PH

✓ Applications: human, mammalian, and other shear or stress-sensitive cells

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SUB500

Floor-Standing Single-Use Bioreactor

✓ Fully scalable from pilot to industrial scale: 50 L – 2000 L

✓ Easy to set up, operate and maintain

✓ Built with a unique upward-inclined stirrer

✓ Applications: human, mammalian and other cells

Applications

Cell & Gene Therapy

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Biologics Production

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Vaccine Development

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Microbial Fermentation

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Functional Food Ingredients

Custom Configuration Guide

1

Architecture

  • Single / twin / parallel vessel

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3

Agitation

  • Impeller

  • Speed

  • Sealing

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5

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Liquid Feed

  • Variable/fixed-speed pump

  • Automatic feeding 4-valve manifold

6

Communication & Automation

  • PLC & HMI

  • SCADA

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7

Basic Monitoring

  • pH

  • DO

  • Temp.

  • Foam

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2

Vessel Config

  • Material

  • Size & aspect ratio

  • Wall

  • Heating method

  • Lighting module

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4

Gas System

  • Gas supply

  • MFC

  • Rotameter

  • Sparger

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8

Advanced Process Analytics

  • OD

  • DCO2

  • VCD

  • ORP

  • Off-gas analysis & heating

  • Weighing module

  • Aseptic sampling device

  • Level detection

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Supporting Equipment

CIP Station

Autoclave

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Air compressor

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Steam Generator

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Chiller

Service & Support

Onsite Installation and Training

Complete Production and Inspection Process

30+ Years Experience of Biotech Engineering Team

Customization Capability

Contact us

Need to speak to a LAB1ST expert? Please complete the form below for your general request, product or service inquiry.

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