BR110 High-throughput parallel bioreactor system
BR110 is a modular, scalable bioreactor platform engineered for early-stage bioprocess development. With working volumes from 0.5 L to 15 L, it enables high-throughput experimentation—running strain screening, media optimization, and feeding strategy validation in parallel, all in a single campaign.
Key Facts
-
Total volume: 0.7-15 L | Working volume: 25-75%
-
Single-wall cylindrical design with flat bottom, constructed with Boro 3.3 glass + electropolished SUS 316L (autoclavable)
-
Siemens S1200 PLC + 15.6" HMI
-
Top-mounted servo-driven mechanical stirrer (5-1000 rpm)
-
2 gas supply (Air, O₂) with:
- up to 2 vvm and 1 vvm
- 1 x Bottom sparger
- 1 x Filter
سمات
High-Throughput Control System
-
Supports synchronized operation of multiple bioreactors, enabling parallel studies across multiple dimensions—including strain screening, media optimization, feeding strategy validation, and pH/DO control—within a single batch.
-
Accelerates process development by covering diverse process conditions in one run, significantly shortening R&D timelines and reducing early-stage development costs.
-
Offers flexible centralized management with independent control per vessel: users can instantly synchronize all online bioreactors via the “One-Click Sync” function, ensuring consistency without sacrificing individual parameter customization.
Exceptional Flexibility and Scalability
-
Modular split-design maximizes valuable benchtop space—keeping your lab organized and workflow efficient.
-
Seamlessly accommodates vessel sizes from 0.7 L to 15 L, eliminating the need for multiple systems and reducing long-term investment while accelerating process development.
-
Solid-state heating and cooling delivers safe, efficient thermal control—no external chillers, heaters, or water lines required.
Simple to Operate, Easy to Use
-
All critical components are integrated into the vessel headplate, enabling quick, tool-free removal and reassembly for effortless cleaning and maintenance.
-
Tool-free, ergonomic connections simplify setup and drastically reduce pre-run preparation time.
-
Premium sensors and pumps from globally recognized brands: high-accuracy pH and DO electrodes, plus variable-speed peristaltic pumps ensure reliable, precise process control.
-
Complete turnkey system — everything you need for immediate operation is included, pre-configured, and ready to run out of the box. No additional accessories to source or purchase.
Flexiable and Realiable Integrated System
Software Capabilities: Intelligent Control & Connected Process Management
-
Synchronized control functions：one-click sync of fermentation parameters across all bioreactors; one-click synchronization of all control switches (e.g., pumps, gas valves, agitation); one-click start for simultaneous fermentation runs
-
Comprehensive control including manual, automatic, sequential, cascaded, conditional, etc. addressing diverse experimental needs with flexible process management.
-
Multiple cascades for DO control integrates agitation speed, oxygen on/off, and feeding for enhanced control responsiveness and fermentation precision.
-
24 programmable recipes with unlimited steps enable fully automated bioprocess execution, reducing manual intervention.
-
One-click calibration of sensors and peristaltic pumps across all online bioreactors—ensuring precise, reliable, and highly parallel process control.
-
Expandable trend monitoring provides real-time bioprocess visualization with customizable data display parameters.
-
Comprehensive data security features 4GB expandable storage with multi-year batch/alarm/operation record retention and export/backup functionality.
-
Three-level authority management with configurable alarm thresholds minimizes operational risks and ensures protocol compliance.
-
Remote connectivity enables real-time monitoring and software updates via PC/mobile devices for off-site process management.
Advanced Culture Vessel: Hygienic Construction & Optimized Performance
-
Single-wall cylindrical vessel combines stainless steel heating base for uniform temperature distribution and efficient cleaning (0.7-2L vessels).
-
Quick-release solid-state exhaust condenser - compact and highly efficient
-
Pharmaceutical-grade materials including electro-polished 316L stainless steel, Boro 3.3 glass, EPDM and Silicon sealings meet stringent hygienic standards.
-
Optimized 2:1 aspect ratio delivers superior mass/heat transfer efficiency to meet demanding bioprocess requirements.
-
Multiple standardized ports support seamless integration of accessories and sensors for flexible system configuration.
-
Knurled screw design enables tool-free assembly and disassembly, streamlining cleaning and maintenance procedures.
Hardware Configuration: Reliable Performance and High-Quality Components
-
Dual gas supply system (Air, O₂) delivers up to 20L/min airflow with roatmeters and solenoid valve for DO regulation.
-
Rotameter and solenoid valve combination for cost-effective aeration strategies
-
Integrated 0.2um PTFE filters (Sartorius®) on gas inlets and exhaust ensure contamination-free operation throughout fermentation cycles.
-
Optimized exhaust condenser effectively recovers volatile compounds while maintaining optimal fermentation conditions.
-
Top-mounted servo agitator delivers maintenance-free performance with instant start/stop response (5-1000rpm) for precise mixing control.
-
Comb-style foam breaker mechanically eliminates surface foam to enhance gas-liquid mass transfer.
-
Adjustable impeller system allows height modification and quick replacement, reducing downtime and operational costs.
-
Full CE certification guarantees compliance with international safety and performance standards.
.jpg)
Machine Magnified - Detailed Angles and Modules
Controller
Sub-unit
Glass Vessel
Exhaust Condenser
Heating & Cooling Jacket
Service
Onsite Installation and Trainig
Complete Production and Inspection Process
30+ Years Experience of Biotech Engineering Team
Customization Capability
.jpg)