Bench-top
Bioreactor System

Next-Gen Bioprocessing Platform with Adaptive Control Architecture

BR200 Series Benchtop Bioreactor

Next-Gen Bioreactor System - A compact, automated solution featuring interchangeable vessels (1L-15L) for seamless scalability. The intuitive 22" touchscreen and remote monitoring enable effortless operation, while automated MFC gas control and modular design ensure precision and easy maintenance. Ideal for efficient, high-accuracy research and process development.

Key Facts

Interchangeable 1 ~15 L vessel with optional additional vessel compatibility enable seamless dual-culture or dual-fermentation process upgrades
Built-in Watson Marlow variable-speed peristaltic pumps
22-inch industrial resistive touchscreen
Precision control with MFCs (mass flow controller)
Culture vessel with heating blanket
Compact footprint with flexible touchscreen placement for optimal lab space utilization.

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Caractéristiques

Easy Operation

Features a 22" glove-friendly touchscreen with intuitive GUI, aviation-grade safety locks, uniform heating, and round-bottom vessel design for optimal mixing, easy cleaning, and contamination-free operation.

Automation & Flexibility

Smart Bioreactor: Modular, multi-vessel system with automated MFC gas control, precision peristaltic pumps, and detachable touchscreen for seamless scaling and reproducible bioprocessing.

Powerful scalability

Module expansion allows a central control unit to oversee and coordinate an additional control unit via Ethernet connection, enabling synchronized dual-vessel operation and accelerating process development

Classification

BR200-M1/C1

Microbial Fermentation & Cell Culture

BR200-M2/C2

Microbial Fermentation & Cell Culture

BR200 Next-Gen Bioreactor System - A compact, automated solution featuring interchangeable vessels (1L-15L) for seamless scalability. The intuitive 22" touchscreen and remote monitoring enable effortless operation, while automated MFC gas control and modular design ensure precision and easy maintenance. Ideal for efficient, high-accuracy research and process development.

Comprehensive control including manual, automatic, sequential, cascaded, conditional, etc. addressing diverse experimental needs with flexible process management.
Multiple cascades for DO control integrates agitation speed, air/oxygen flows, and feeding for enhanced control responsiveness and fermentation precision.
24 programmable recipes with unlimited steps enable fully automated bioprocess execution, reducing manual intervention.
On-the-fly calibration ensures sensor and pump accuracy, maintaining reliable process control throughout operations.
Expandable trend monitoring provides real-time bioprocess visualization with customizable data display parameters.
Comprehensive data security features 4GB expandable storage with multi-year batch/alarm/operation record retention and export/backup functionality.
Three-level authority management with configurable alarm thresholds minimizes operational risks and ensures protocol compliance.
Remote connectivity enables real-time monitoring and software updates via PC/mobile devices for off-site process management.

Model: BR200-M1

Culture Vessel: 1 * 1 L, 2 L, 3 L, 5 L, 7 L, 10 L, 15 L

Controller Capacity: Single vessel

Application: Microbial Fermentation

Model: BR200-C1

Culture Vessel: 1 * 1 L, 2 L, 3 L, 5 L, 7 L, 10 L, 15 L

Controller Capacity: Single vessels

Application: Cell culture

Model: BR200-M2

Culture Vessel: 2 * 1 L, 2 L, 3 L, 5 L, 7 L, 10 L, 15 L

Controller Capacity: Twin vessels

Application: Microbial Fermentation

Model: BR200-C2

Culture Vessel: 2 * 1 L, 2 L, 3 L, 5 L, 7 L, 10 L, 15 L

Controller Capacity: Twin vessels

Application: Cell culture

For detailed technical parameters, please contact us or download the specifications.

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Microbial Fermentation - O2-Enrichment

Two Gas Sources (Air & Oxygen) + Single Bottom Sparger

Flow rate: automatically adjusted via MFC (Mass Flow Controller
Gas Mixing & Delivery:
- The two gas streams merge into a single line.
- Pass through a 0.2 μm sterile filter for contamination control

Cell Culture - Additive Flow

3 Gas Sources (Air, CO₂, O₂) + Dual Delivery (Overlay & Sparger)

Air Supply – Overlay (Surface Aeration)
- A split air stream is adjusted via MFC
- Filtered through a 0.2 μm sterile filter.
- Delivered to the headspace (overlay) of the vessel.
Automated Gas Blending – Bottom Sparger
- Gases: Air, O₂, CO₂. Each gas is controlled by an individual MFC
- The selected gas merges into a single line
- The blended gas passes through a 0.2 μm sterile filter.
- Enters the vessel via a bottom ring sparger for efficient gas-liquid contact.

Powerful Hardware Configuration

22-inch industrial resistive touchscreen, easy-to-use and reliable operation even while wearing laboratory gloves;
A full set of Hamiltion / Metteler sensors with high precision, supporting repeated sterilization, and facilitating process development and optimization;
Servo Motors: High-precision, maintenance-free, low-noise servo motors for long-term stable operation;
Watson Marlow variable-speed Peristaltic Pumps for fast tubing installations;
Individual MFCs automate and precisely regulate all gas inputs
Quick-connect couplings make it easy to attach all cables and supplies to the culture vessels;
All inlets and ports for cooling water, process gases, electricity, Ethernet, and potential-free alarm contacts are located on the side panel of the control tower

Mature Culture Vessel Design

Single-wall cylindrical vessel combines electric heating blanket for uniform temperature distribution and efficient cleaning.
Pharmaceutical-grade materials including electro-polished 316L stainless steel, Boro 3.3 glass, EPDM and Silicon sealings meet stringent hygienic standards.
Optimized 2:1 aspect ratio delivers superior mass/heat transfer efficiency to meet demanding bioprocess requirements.
Multiple standardized ports support seamless integration of accessories and sensors for flexible system configuration.
Knurled screw design enables tool-free assembly and disassembly, streamlining cleaning and maintenance procedures.

Complete Software Functions

Multi-mode Control: Manual/auto/sequential/cascade/conditional modes for flexible process management.
Smart DO Cascade: Integrates agitation/O₂/feeding for precise fermentation control.
24+ Program Recipes: Unlimited-step automation reduces manual operation.
Live Calibration: Ensures real-time sensor/pump accuracy.
Custom Trend Monitoring: Real-time data visualization with adjustable parameters.
Secure Data Storage: 4GB expandable memory with batch/alarm/operation records.
3-tier Access Control: Configurable permissions & alarm thresholds for compliance.
Remote Monitoring: Real-time control/updates via PC/mobile devices.

Gas: Nitrogen, Methane, etc.
Scale: Tank weight / replenishing
Sampling: Sterile sampling device
Remote Function: Option to upgrade remote monitoring and screen mirroring.
Exhaust Gas Analysis: Exhaust gas analyzer for O₂ and CO₂
Exhaust Gas Heating: Exhaust heater

Vessel Type: Double-wall round bottom cylindrical tank + water jacket temperature control temperature control
Drive: Top magnetic drive, top machanical stirring
Height-to-diameter ratio: 1.5:1 | 2.5:1 | 3:1
Sparger type: Microsparger
Material: 2205 duplex stainless steel/titanium [Wetted Part]; Stainless steel 304 housing
Impeller: Customizable blades from different options (Spin filter, Cell-lift）

Communication: SCADA
Power: 110V (± 10%), 60Hz, single phase
pH electrode: Mettler Toledo brand
DO electrode: Mettler Toledo brand, optical electrode
More sensors: DCO2 sensor, VCD sensor, OD sensor, etc.
Peristaltic pump: More peristaltic pumps for different functions